Ed Boyden, Ph.D., Principal Investigator
Expansion microscopy: physical magnification with nanoscale precision
Pumby: programmable, modular RNA binding proteins
SiRIs: spatial multiplexing of fluorescent reporters for imaging signaling network dynamics
SomaGCaMP: soma-targeted calcium indicators for precision neural population imaging
SomArchon: voltage indicator for population neural activity imaging
Archon1: well-localized, high-sensitivity, photostable fluorescent voltage indicator
Lightfield microscopy: fast 3-D neural imaging
Autopatching: robotic patch clamp in live brain
ChromeQ: optogenetic activation with reduced proton and calcium currents
soCoChR: soma-targeted, high-amplitude channelrhodopsin
Jaws: red light-drivable halorhodopsin
Chrimson: red light-drivable channelrhodopsin
Chronos: high-speed, light-sensitive, channelrhodopsin
CoChR: large-current channelrhodopsin
Lumitoxins: light-actuated tethered toxin architecture
ArchT: light-sensitive archaerhodopsin
Arch: archaerhodopsin (light-driven proton pump)
Mac: light-driven proton pump of L. maculans
ChR2-2A-Halo: channelrhodopsin-halorhodopsin gene fusions
Halo/NpHR: halorhodopsin (light-driven chloride pump)
ChR2: channelrhodopsin-2 (light-driven cation channel)
Glial optogenetic tools
Accessory plasmids for optogenetics
Lentivirus production for high-titer, cell-specific, in vivo neural labeling
Versatile, but Manually-Assembled, Optical Fiber/Laser System for In Vivo Optogenetics
Very Simple Off-The-Shelf Systems for In Vivo Optogenetics
Closed-loop, ultraprecise, automated craniotomies